Cancer is considered one of the most vicious diseases as it affects millions of people every year. This is the most common reason behind death as according to data the second major reason which causes death in humans. We have made quite a huge contribution in the field of research to understand every aspect of the cancer. The cancer happens due to cells which are abnormal and start to grow. There are numerous changes that take place in the genome in a dynamic way. This leads to turning cells into cancer. This will direct to turning other cells and tissues and further far off tissues to circulate cancer.
There are innumerable ways that treatment of cancer can take place. First is surgery which can be opted by some doctors, radiation therapy is also a choice , laser therapy utilized by numerous healthcare experts to treat cancer, combination therapy which means combining two and more therapy to remove cancer. There are multiple researches that are conducted to eradicate cancer based on ideas and knowledge of tumor biology and genetics molecular. The most popular treatment among presently available options is chemotherapy, although it has the biggest drawback too. The drug resistance can be reason not to successfully achieve the result of removing cancer. The data indicating that more than 90% treatment of chemotherapy has to see failure during the phase of invasion and metastasis due to drug resistance.
During the cancer treatment, MDR can happen to numerous cancer patients, Multidrug Resistance, it means that the cancer patient is resistant to various drugs given to remove cancer. The comparable case can be antibiotic resistance when bacterial infection happens.
There are two types of treatment which can be given to cancer patient
One is called local treatments which have options such as radiation and surgery. The second treatment which is more popular is called systematic treatments such as targeted therapy, hormone therapy and well known chemotherapy.
The option of such systematic therapy utilized when the cancer is at the advanced stage or metastatic.
MDR happens due to elevated disposal of efflux drugs which are designed for chemotherapy. It further reduces absorption and effectiveness of drugs. In simple terms the drugs given during the chemotherapy do not get properly absorbed that’s the reason why the drugs will not work on the patient’s cancer.
If we want the drugs to work, we need to remove the issue of drug resistance as it will create a situation where no therapy works for cancer. If we will work on drug resistance and find potential solutions it will also increase the effectiveness of drugs as well.
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